Human microbiota dysbiosis after SARS-CoV-2 infection have the potential to predict disease prognosis

  • Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239–42.

    Article
    CAS
    PubMed

    Google Scholar

  • Kesheh MM, Hosseini P, Soltani S, Zandi M. An overview on the seven pathogenic human coronaviruses. Rev Med Virol. 2022;32(2): e2282.

    Article
    CAS
    PubMed

    Google Scholar

  • Zandi M. ORF9c and ORF10 as accessory proteins of SARS-CoV-2 in immune evasion. Nat Rev Immunol. 2022;22(5):331–331.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Hernandez-Teran A, Mejia-Nepomuceno F, Herrera MT, Barreto O, Garcia E, Castillejos M, Boukadida C, Matias-Florentino M, Rincon-Rubio A, Avila-Rios S, et al. Dysbiosis and structural disruption of the respiratory microbiota in COVID-19 patients with severe and fatal outcomes. Sci Rep. 2021;11(1):21297.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Mizutani T, Ishizaka A, Koga M, Ikeuchi K, Saito M, Adachi E, Yamayoshi S, Iwatsuki-Horimoto K, Yasuhara A, Kiyono H et al. Correlation Analysis between Gut Microbiota Alterations and the Cytokine Response in Patients with Coronavirus Disease during Hospitalization. Microbiol Spectr. 2022;10(2):e0168921.

  • Buttenschon J, Vogt S, Mattner J. Compartmentalized immune responses and the local microbiota determine mucosal and systemic immunity against SARS-CoV-2. Cell Mol Immunol. 2022;19(2):130–2.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • Xu R, Liu P, Zhang T, Wu Q, Zeng M, Ma Y, Jin X, Xu J, Zhang Z, Zhang C. Progressive deterioration of the upper respiratory tract and the gut microbiomes in children during the early infection stages of COVID-19. J Genet Genomics. 2021;48(9):803–14.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Mazzarelli A, Giancola ML, Farina A, Marchioni L, Rueca M, Gruber CEM, Bartolini B, Ascoli Bartoli T, Maffongelli G, Capobianchi MR, et al. 16S rRNA gene sequencing of rectal swab in patients affected by COVID-19. PLoS ONE. 2021;16(2): e0247041.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Gu S, Chen Y, Wu Z, Chen Y, Gao H, Lv L, Guo F, Zhang X, Luo R, Huang C, et al. Alterations of the Gut Microbiota in Patients With Coronavirus Disease 2019 or H1N1 Influenza. Clin Infect Dis. 2020;71(10):2669–78.

    Article
    CAS
    PubMed

    Google Scholar

  • Tao W, Zhang G, Wang X, Guo M, Zeng W, Xu Z, Cao D, Pan A, Wang Y, Zhang K, et al. Analysis of the intestinal microbiota in COVID-19 patients and its correlation with the inflammatory factor IL-18. Med Microecol. 2020;5: 100023.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • Lv LX, Gu SL, Jiang HY, Yan R, Chen YF, Chen YB, Luo R, Huang CJ, Lu HF, Zheng BW et al. Gut mycobiota alterations in patients with COVID-19 and H1N1 infections and their associations with clinical features. Commun Biol. 2021;4(1):480.

  • Chen Y, Gu S, Chen Y, Lu H, Shi D, Guo J, Wu WR, Yang Y, Li Y, Xu KJ, et al. Six-month follow-up of gut microbiota richness in patients with COVID-19. Gut. 2022;71(1):222–5.

    Article
    PubMed

    Google Scholar

  • Zhou Y, Zhang J, Zhang D, Ma WL, Wang X. Linking the gut microbiota to persistent symptoms in survivors of COVID-19 after discharge. J Microbiol. 2021;59(10):941–8.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Newsome RC, Gauthier J, Hernandez MC, Abraham GE, Robinson TO, Williams HB, Sloan M, Owings A, Laird H, Christian T, et al. The gut microbiome of COVID-19 recovered patients returns to uninfected status in a minority-dominated United States cohort. Gut Microbes. 2021;13(1):1–15.

    Article
    CAS
    PubMed

    Google Scholar

  • Hurst JH, McCumber AW, Aquino JN, Rodriguez J, Heston SM, Lugo DJ, Rotta AT, Turner NA, Pfeiffer TS, Gurley TC, et al. Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults. Clin Infect Dis. 2022;75(1):e928–37.

  • Rueca M, Fontana A, Bartolini B, Piselli P, Mazzarelli A, Copetti M, Binda E, Perri F, Gruber CEM, Nicastri E et al. Investigation of Nasal/Oropharyngeal Microbial Community of COVID-19 Patients by 16S rDNA Sequencing. Int J Environ Res Public Health. 2021;18(4):2174.

  • Ventero MP, Cuadrat RRC, Vidal I, Andrade BGN, Molina-Pardines C, Haro-Moreno JM, Coutinho FH, Merino E, Regitano LCA, Silveira CB, et al. Nasopharyngeal Microbial Communities of Patients Infected With SARS-CoV-2 That Developed COVID-19. Front Microbiol. 2021;12: 637430.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • Nagata N, Takeuchi T, Masuoka H, Aoki R, Ishikane M, Iwamoto N, Sugiyama M, Suda W, Nakanishi Y, Terada-Hirashima J, et al. Human Gut Microbiota and Its Metabolites Impact Immune Responses in COVID-19 and Its Complications. Gastroenterology. 2023;164(2):272–88.

    Article
    CAS
    PubMed

    Google Scholar

  • Sarkar A, Harty S, Moeller AH, Klein SL, Erdman SE, Friston KJ, Carmody RN. The gut microbiome as a biomarker of differential susceptibility to SARS-CoV-2. Trends Mol Med. 2021;27(12):1115–34.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Khan M, Mathew BJ, Gupta P, Garg G, Khadanga S, Vyas AK, Singh AK. Gut Dysbiosis and IL-21 Response in Patients with Severe COVID-19. Microorganisms. 2021;9(6):1292.

  • Moreira-Rosario A, Marques C, Pinheiro H, Araujo JR, Ribeiro P, Rocha R, Mota I, Pestana D, Ribeiro R, Pereira A, et al. Gut Microbiota Diversity and C-Reactive Protein Are Predictors of Disease Severity in COVID-19 Patients. Front Microbiol. 2021;12: 705020.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • Estaki M, Jiang L, Bokulich NA, McDonald D, Gonzalez A, Kosciolek T, Martino C, Zhu Q, Birmingham A, Vazquez-Baeza Y, et al. QIIME 2 enables comprehensive End-to-End analysis of diverse microbiome data and comparative studies with publicly available data. Curr Protoc Bioinformatics. 2020;70(1): e100.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJ, Holmes SP. DADA2: High-resolution sample inference from Illumina amplicon data. Nat Methods. 2016;13(7):581–3.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Katoh K, Misawa K, Kuma K, Miyata T. MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform. Nucleic Acids Res. 2002;30(14):3059–66.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Price MN, Dehal PS, Arkin AP. FastTree 2–approximately maximum-likelihood trees for large alignments. PLoS ONE. 2010;5(3): e9490.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • McDonald D, Price MN, Goodrich J, Nawrocki EP, DeSantis TZ, Probst A, Andersen GL, Knight R, Hugenholtz P. An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea. ISME J. 2012;6(3):610–8.

    Article
    CAS
    PubMed

    Google Scholar

  • Bokulich NA, Kaehler BD, Rideout JR, Dillon M, Bolyen E, Knight R, Huttley GA, Caporaso JG. Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2 ‘ s q2-feature-classifier plugin. Microbiome. 2018;6(1):90.

  • Liu C, Cui Y, Li X, Yao M: microeco: an R package for data mining in microbial community ecology. FEMS Microbiol Ecol 2021, 97(2).

  • Tian Y, Sun KY, Meng TQ, Ye Z, Guo SM, Li ZM, Xiong CL, Yin Y, Li HG, Zhou LQ. Gut microbiota may not be fully restored in recovered COVID-19 patients after 3-month recovery. Front Nutr. 2021;8: 638825.

    Article
    PubMed
    PubMed Central

    Google Scholar

  • Kim HN, Joo EJ, Lee CW, Ahn KS, Kim HL, Park DI, Park SK. Reversion of Gut Microbiota during the Recovery Phase in Patients with Asymptomatic or Mild COVID-19: Longitudinal Study. Microorganisms. 2021;9(6):1237.

  • Gaibani P, D’Amico F, Bartoletti M, Lombardo D, Rampelli S, Fornaro G, Coladonato S, Siniscalchi A, Re MC, Viale P, et al. The Gut Microbiota of Critically Ill Patients With COVID-19. Front Cell Infect Microbiol. 2021;11: 670424.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Gupta A, Karyakarte R, Joshi S, Das R, Jani K, Shouche Y, Sharma A. Nasopharyngeal microbiome reveals the prevalence of opportunistic pathogens in SARS-CoV-2 infected individuals and their association with host types. Microbes Infect. 2022;24(1): 104880.

    Article
    CAS
    PubMed

    Google Scholar

  • Merenstein C, Liang G, Whiteside SA, Cobian-Guemes AG, Merlino MS, Taylor LJ, Glascock A, Bittinger K, Tanes C, Graham-Wooten J, et al. Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome. mBio. 2021;12(4):e0177721.

  • Ren Z, Wang H, Cui G, Lu H, Wang L, Luo H, Chen X, Ren H, Sun R, Liu W, et al. Alterations in the human oral and gut microbiomes and lipidomics in COVID-19. Gut. 2021;70(7):1253–65.

    Article
    CAS
    PubMed

    Google Scholar

  • Schnorr SL, Candela M, Rampelli S, Centanni M, Consolandi C, Basaglia G, Turroni S, Biagi E, Peano C, Severgnini M, et al. Gut microbiome of the Hadza hunter-gatherers. Nat Commun. 2014;5:3654.

    Article
    CAS
    PubMed

    Google Scholar

  • Zaura E, Brandt BW, Teixeira de Mattos MJ, Buijs MJ, Caspers MP, Rashid MU, Weintraub A, Nord CE, Savell A, Hu Y, et al. Same Exposure but Two Radically Different Responses to Antibiotics: Resilience of the Salivary Microbiome versus Long-Term Microbial Shifts in Feces. mBio. 2015;6(6):e01693–15.

  • Tuddenham SA, Koay WLA, Zhao N, White JR, Ghanem KG, Sears CL. The Impact of Human Immunodeficiency Virus Infection on Gut Microbiota α-Diversity: An Individual-level Meta-analysis. Clin Infect Dis. 2020;70(4):615–27.

  • Maynard C, Weinkove D. The Gut Microbiota and Ageing. Subcell Biochem. 2018;90:351–71.

    Article
    CAS
    PubMed

    Google Scholar

  • David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, Ling AV, Devlin AS, Varma Y, Fischbach MA, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature. 2014;505(7484):559–63.

    Article
    CAS
    PubMed

    Google Scholar

  • Midani FS, Weil AA, Chowdhury F, Begum YA, Khan AI, Debela MD, Durand HK, Reese AT, Nimmagadda SN, Silverman JD, et al. Human Gut Microbiota Predicts Susceptibility to Vibrio cholerae Infection. J Infect Dis. 2018;218(4):645–53.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Barberio B, Facchin S, Patuzzi I, Ford AC, Massimi D, Valle G, Sattin E, Simionati B, Bertazzo E, Zingone F, et al. A specific microbiota signature is associated to various degrees of ulcerative colitis as assessed by a machine learning approach. Gut Microbes. 2022;14(1):2028366.

  • Gou W, Fu Y, Yue L, Chen GD, Cai X, Shuai M, Xu F, Yi X, Chen H, Zhu Y, et al. Gut microbiota, inflammation, and molecular signatures of host response to infection. J Genet Genomics. 2021;48(9):792–802.

    Article
    CAS
    PubMed

    Google Scholar

  • Rashidi A, Ebadi M, Weisdorf DJ, Costalonga M, Staley C. No evidence for colonization of oral bacteria in the distal gut in healthy adults. P Natl Acad Sci USA. 2021;118(42):e2114152118.

  • Gupta A, Bhanushali S, Sanap A, Shekatkar M, Kharat A, Raut C, Bhonde R, Shouche Y, Kheur S, Sharma A. Oral dysbiosis and its linkage with SARS-CoV-2 infection. Microbiol Res. 2022;261: 127055.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Rattanaburi S, Sawaswong V, Chitcharoen S, Sivapornnukul P, Nimsamer P, Suntronwong N, Puenpa J, Poovorawan Y, Payungporn S. Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patients. Exp Biol Med (Maywood). 2022;247(5):409–15.

    Article
    CAS
    PubMed

    Google Scholar

  • Liu J, Liu S, Zhang Z, Lee X, Wu W, Huang Z, Lei Z, Xu W, Chen D, Wu X, et al. Association between the nasopharyngeal microbiome and metabolome in patients with COVID-19. Synthetic and systems biotechnology. 2021;6(3):135–43.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

  • Ventero MP, Cuadrat RRC, Vidal I, Andrade BGN, Molina-Pardines C, Haro-Moreno JM, Coutinho FH, Merino E, Regitano LCA, Silveira CB, et al. Nasopharyngeal Microbial Communities of Patients Infected With SARS-CoV-2 That Developed COVID-19. Frontiers In Microbiology. 2021;12:637430.

  • Tett A, Pasolli E, Masetti G, Ercolini D, Segata N. Prevotella diversity, niches and interactions with the human host. Nat Rev Microbiol. 2021;19(9):585–99.

    Article
    CAS
    PubMed

    Google Scholar

  • Fujita K, Takata I, Sugiyama H, Suematsu H, Yamagishi Y, Mikamo H. Antimicrobial susceptibilities of clinical isolates of the anaerobic bacteria which can cause aspiration pneumonia. Anaerobe. 2019;57:86–9.

    Article
    CAS
    PubMed

    Google Scholar

  • Zhou H, Shen Y, Shen Q, Zhou J: Thoracic empyema caused by Prevotella spp. diagnosed using 16S rDNA sequence analysis. Clin Respir J 2015, 9(1):121–124.

  • Tamanai-Shacoori Z, Le Gall-David S, Moussouni F, Sweidan A, Polard E, Bousarghin L, Jolivet-Gougeon A: SARS-CoV-2 and Prevotella spp.: friend or foe? A systematic literature review. J Med Microbiol. 2022;71(5):001520.

  • Haran JP, Bradley E, Zeamer AL, Cincotta L, Salive MC, Dutta P, Mutaawe S, Anya O, Meza-Segura M, Moormann AM, et al. Inflammation-type dysbiosis of the oral microbiome associates with the duration of COVID-19 symptoms and long COVID. JCI Insight. 2021;6(20):e152346.

  • Khan AA, Khan Z. COVID-2019-associated overexpressed Prevotella proteins mediated host-pathogen interactions and their role in coronavirus outbreak. Bioinformatics. 2020;36(13):4065–9.

    Article
    CAS
    PubMed

    Google Scholar

  • Larsen JM. The immune response to Prevotella bacteria in chronic inflammatory disease. Immunology. 2017;151(4):363–74.

    Article
    CAS
    PubMed
    PubMed Central

    Google Scholar

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