18th annual blood drive held in memory of fallen NYPD Detective Dillon Stewart

Nov 29, 2023, 1:55amUpdated 18m ago Dozens gathered at the NYPD 70th Precinct Tuesday afternoon to remember fallen Detective Dillon Stewart on the 18th anniversary of his death. Stewart was killed in the line of duty in 2005, after he was shot while attempting to pull over someone driving a stolen vehicle. Stewart left behind his beloved wife, Leslyn, and two young daughters. Eighteen years later, the tradition of organizing a blood drive around the anniversary of his death continues to be the way the NYPD and Stewart family honor the late detective’s legacy. “I know that the night my dad was killed, he needed lots of blood. It means so much to see people continue to give in his honor”, said Samantha Stewart, Detective Dillon Stewart’s youngest daughter. Stewart’s eldest daughter, Alexis Stewart, has since followed in her father’s footsteps, now serving as a civilian working with the NYPD in Lower Manhattan. “I know I always have him close to my heart,” she said as she touched a locket with her father’s picture on her neck on one side, and shield number on the other. The Stewart family says they hope to continue this tradition for many years to come. Share this story

Valencia High School’s MSA students work to save lives

Rylee Kelemen Rylee Kelemen (née Holwager) joined The Signal team in June 2022, but has lived in Santa Clarita her entire life. She loves to tell the people’s stories and keep the public informed. She is a graduate of California State University, Northridge and was the Social Media Editor at her time with The Daily Sundial. Have a story to share? Email Rylee at [email protected].

ENHYPEN Score Sixth Top 10 on Album Sales Chart With ‘Orange Blood’

ENHYPEN score their sixth top 10 on Billboard’s Top Album Sales chart (dated Dec. 2), as the Korean pop ensemble’s Orange Blood bows at No. 2. The set sold 87,000 copies in the U.S. in the week ending Nov. 23, according to Luminate. Explore See latest videos, charts and news See latest videos, charts and news Also in the top 10 of the new Top Album Sales chart, Dolly Parton notches her first No. 1 on the 32-year-old list with the arrival of Rockstar; Taylor Swift has half of the top 10 thanks to sale pricing and promotions for Black Friday, and Cher’s Christmas vaults 23-10 after its release on vinyl. Billboard’s Top Album Sales chart ranks the top-selling albums of the week based only on traditional album sales. The chart’s history dates back to May 25, 1991, the first week Billboard began tabulating charts with electronically monitored piece count information from SoundScan, now Luminate. Pure album sales were the sole measurement utilized by the Billboard 200 albums chart through the list dated Dec. 6, 2014, after which that chart switched to a methodology that blends album sales with track equivalent album units and streaming equivalent album units. For all chart news, follow @billboard and @billboardcharts on both Twitter and Instagram. Of the 87,000 copies sold of Orange Blood, physical sales comprise 86,000 (all on CD) and digital download album sales comprise 1,000. Its sales were bolstered by its availability across a dozen collectible CD packages (including exclusive versions sold by Barnes & Noble, Target and Walmart; all with branded merchandise inside, some with randomized elements). As previously reported, Parton’s Rockstar rules Top Album Sales with her biggest sales week of the modern era (since Luminate began electronically tracking sales in 1991), with 118,500 copies sold. Its sales were enhanced by a variety of iterations available on vinyl and CD. Swift has half of the top 10 on Top Album Sales for a third time, thanks to sale pricing and promotions previewing the Black Friday shopping holiday on Nov. 24. (Swift previously had five of the top 10 on the Nov. 11-dated list, and six of the top 10 on the July 22-dated chart.) On the latest Top Album Sales ranking, Swift’s 1989 (Taylor’s Version) falls 2-3 (64,000; down 7%), Folklore jumps 14-6 (20,000; up 77%), Midnights rallies 11-7 (19,000; up 57%), Lover leaps 16-8 (18,000; up 80%) and Speak Now (Taylor’s Version) shoots 15-9 (17,000; up 72%). All are former No. 1s on the tally. Stray Kids’ ROCK-STAR falls 1-4 in its second week on Top Album Sales, selling 46,000 copies (down 78%). Jung Kook’s chart-topping Golden dips 4-5 with 20,000 sold (down 42%). Rounding out the top 10 is Cher’s Christmas, which returns to the region, zipping 23-10 with 14,000 sold (up 82%) following the set’s release on vinyl on Nov. 17. It sold a little over 6,000 copies on vinyl. Christmas debuted and peaked at No. 5 on the Nov. 4-dated chart. In the week ending Nov. 23, there were 2.34 million albums sold in the U.S. (up 1.7% compared to the previous week). Of that sum, physical albums (CDs, vinyl LPs, cassettes, etc.) comprised 1.98 million (up 2.6%) and digital albums comprised 361,000 (down 3.1%). There were 923,000 CD albums sold in the week ending Nov. 23 (down 3.4% week-over-week) and 1.046 million vinyl albums sold (up 8.6%). Year-to-date CD album sales stand at 31.921 million (up 2.9% compared to the same time frame a year ago) and year-to-date vinyl album sales total 41.441 million (up 17.1%). Overall year-to-date album sales total 90.474 million (up 6.1% compared to the same year-to-date time frame a year ago). Year-to-date physical album sales stand at 73.857 million (up 10.4%) and digital album sales total 16.617 million (down 9.4%).

Blood drive Thursday in Branchville

A blood drive will be held from 10 a.m. to 3 p.m. Thursday, Nov. 30 at American Legion Post 157, 325 Route 206, Branchville. Donations are critical to the blood supply as the holiday season draws near because blood donations often decline then. Donors of all blood types are urged to give, especially type O blood donors and those giving platelets. To celebrate the 20th anniversary of the holiday move “Elf,” people who donate blood, platelets or plasma to the Red Cross between Nov. 10 and 30 will receive officially licensed “Elf” and Red Cross socks while supplies last. For information, call 1-800-RED CROSS (1-800-733-2767).

Rise of the Indian Challengers in the Global Cardiovascular Devices Market

<!– –> Rise of the Indian Challengers in the Global Cardiovascular Devices Market, ET HealthWorld <!– –> <!– –> <!– We have updated our terms and conditions and privacy policy Click “Continue” to accept and continue with ET HealthWorld –> <!– X We use cookies to ensure best experience for you We use cookies and other tracking technologies to improve your browsing experience on our site, show personalize content and targeted ads, analyze site traffic, and understand where our audience is coming from. You can also read our privacy policy, We use cookies to ensure the best experience for you on our website. By choosing I accept, or by continuing being on the website, you consent to our use of Cookies and Terms & Conditions. Analytics and Performance Cookies Targeted and Advertising Cookies –> <!– skip to main content –> <section class="container article-section status_prime_article single-post currentlyInViewport inViewPort" id="news_dtl_105572044" data-article="0" page-title="Rise of the Indian Challengers in the Global Cardiovascular Devices Market" data-href="https://health.economictimes.indiatimes.com/news/medical-devices/rise-of-the-indian-challengers-in-the-global-cardiovascular-devices-market/105572044" data-msid="105572044" data-news="{"link":"/news/medical-devices/rise-of-the-indian-challengers-in-the-global-cardiovascular-devices-market/105572044","seolocation":"/news/medical-devices/rise-of-the-indian-challengers-in-the-global-cardiovascular-devices-market/105572044","seolocationalt":"/news/medical-devices/rise-of-the-indian-challengers-in-the-global-cardiovascular-devices-market/105572044","seometatitle":false,"seo_meta_description":"The Indian domestic market is now poised for much faster growth compared to its global peers due to its considerably small base versus the size of its population. Deepening insurance penetration, rising affordability and the widening of patient pool driven by government sponsored schemes are some of the key factors driving this growth. ","canonical_url":false,"url_seo":"/news/medical-devices/rise-of-the-indian-challengers-in-the-global-cardiovascular-devices-market/105572044","category_name":"Medical Devices","category_link":"/news/medical-devices","category_name_seo":"medical-devices","updated_at":"2023-11-29 05:58:33","artexpdate":false,"agency_name":"ETHealthWorld","agency_link":"/agency/88675629/ETHealthWorld","read_duration":"4 min","no_index_no_follow":false,"keywords":[{"id":1832783,"name":"ujjwal singh","type":"General","weightage":80,"keywordseo":"ujjwal-singh","botkeyword":false,"source":"Orion","link":"/tag/ujjwal+singh"},{"id":3727552,"name":"meril life sciences","type":"General","weightage":80,"keywordseo":"meril-life-sciences","botkeyword":false,"source":"Orion","link":"/tag/meril+life+sciences"},{"id":1715229,"name":"smt","type":"General","weightage":50,"keywordseo":"smt","botkeyword":false,"source":"Orion","link":"/tag/smt"},{"id":53564,"name":"southeast asia","type":"General","weightage":50,"keywordseo":"southeast-asia","botkeyword":false,"source":"Orion","link":"/tag/southeast+asia"},{"id":15378315,"name":"Cardiovascular devices","type":"General","weightage":20,"keywordseo":"Cardiovascular-devices","botkeyword":false,"source":"Orion","link":"/tag/cardiovascular+devices"},{"id":1069791,"name":"translumina","type":"General","weightage":20,"keywordseo":"translumina","botkeyword":false,"source":"Orion","link":"/tag/translumina"},{"id":5949510,"name":"percutaneous coronary interventions","type":"General","weightage":20,"keywordseo":"percutaneous-coronary-interventions","botkeyword":false,"source":"Orion","link":"/tag/percutaneous+coronary+interventions"},{"id":1544318,"name":"stent implants","type":"General","weightage":20,"keywordseo":"stent-implants","botkeyword":false,"source":"Orion","link":"/tag/stent+implants"}],"read_industry_leader_count":false,"read_industry_leaders":false,"embeds":[{"title":"Over the last six years, most Indian stent manufacturers have seen exponential growth in international markets and have established a strong foothold in multiple countries.","type":"image","caption":false,"elements":[]}],"thumb_big":"https://etimg.etb2bimg.com/thumb/msid-105572044,imgsize-132670,width-1200,height=765,overlay-ethealth/medical-devices/rise-of-the-indian-challengers-in-the-global-cardiovascular-devices-market.jpg","thumb_small":"https://etimg.etb2bimg.com/thumb/img-size-132670/105572044.cms?width=150&height=112","time":"2023-11-29 05:58:12","is_live":false,"prime_id":0,"highlights":[],"highlights_html":"","also_read_available":false,"body":" by Ujjwal Singh The Indian Cardiovascular devices landscape witnessed a turning point in November 2018, when the Government of India notified price control on stents, bringing down the prices by more than 80%. With a current market size of ~USD 200 million, this market is slated to be one of the fastest growing in the world, growing at a staggering 14-15% CAGR over next decade. Let’s find out what’s driving this growth. A stent in timeHistorically speaking, it’s interesting to note that India’s medical devices market was dominated by global majors. This heavy reliance on expensive imported devices hindered accessibility to life-saving interventions, with only a fraction of the population receiving essential procedures, such as percutaneous coronary interventions (PCI). However, post implementation of the price cap, there was an over 30% surge in the number of stent implants in just 12 months. The price control combined with inclusion of stent implants in government schemes led to both a multi-fold increase in stent implants and a remarkable shift in the Indian landscape, with Indian players increasing their market share from 35% to an impressive 60%. Global majors such as Abbott Vascular, Boston Scientific, and Medtronic, had to adapt to the revised pricing, allowing local players, such as, SMT, Translumina, and Meril room to grow their share by providing high-quality products but at a much lower cost. India’s advantage in manufacturing, with low labour costs and a pool of skilled talent, further fuelled the growth of domestic production. The Indian domestic market is now poised for much faster growth compared to its global peers due to its considerably small base versus the size of its population. Deepening insurance penetration, rising affordability and the widening of patient pool driven by government sponsored schemes are some of the key factors driving this growth. Global exports are also likely to play a critical role for domestic medical devices manufacturers, particularly those with high quality standards and in-house capabilities. Expanding into global marketsThe pricing reforms coincided with two big milestones in the Indian stent space – the successful completion of first clinical trial in India by SMT Pvt. Ltd and the launch of the first bioabsorbable stent by Meril Life Sciences. These two episodes provided a perfect launch pad to succeed in the international markets via increased acceptability and reliability of Indian manufactured cardiology devices. This led to a successful expansion by select Indian manufacturers across global markets, including Europe, Southeast Asia, Africa and the Middle East. Strong growth, global expansion and, rising profitability led to increased interest from financial sponsors, including Private Equity investors. This enabled Indian players to build world-class R&D and manufacturing infrastructure, while maintaining the local cost advantage. With additional capital and capabilities, select Indian manufacturers have been able to conduct expensive global trials and establish techno-commercial teams to navigate the complex regulatory and marketing processes in developed markets. Over the last six years, most Indian stent manufacturers have seen exponential growth in international markets and have established a strong foothold in multiple countries. Next Opportunity: Foray into the Structural Heart Devices marketWhile Indian players enjoyed success in stents in both domestic as well as international markets, structural heart devices market is still a nascent play for most. In recent years, many of the global CVD leaders have been shifting their focus towards structural heart devices due to significantly higher sophistication and realization. While the global structural heart devices market stood at USD 5.6 billion in 2020 and is expected to grow at 13% over the next 5 years, India’s structural heart market stands at a mere USD 12.4 million and is projected to grow at a 31% CAGR due to a very low base. In India, the limited penetration can be attributed to factors like affordability, accessibility, and a shortage of specialists capable of conducting these complex procedures. Per our interaction with few leading clinicians, we understand that minimally invasive procedures for structural heart disease can cost up to INR 30 lakhs using MNC products and nearly half using products from Indian players. On top of this high treatment cost, this procedure is currently not reimbursed by any government schemes, thus making it out of reach for most Indians. The success of Indian players in the stent market provides an ideal thesis for their foray into the structural heart devices market. With established distribution networks in both domestic and global markets, Indian companies can leverage their strengths to introduce new products through organic development and/or strategic acquisitions. With

Findings challenge standard understanding of COVID-19 infection

Some viruses move between species. For example, SARS-CoV-2, the virus that causes COVID-19, can spill over from humans to mink, an agricultural species, and then spill back from mink to humans. Spill back is a concern because SARS-CoV-2 can mutate in the mink and come back to humans in a more virulent form. Both spill over and spill back of SARS-CoV-2 have been reported on mink farms in the United States and Europe. To address these issues, a research team at the University of California, Riverside, has now studied zoonosis — the interspecies transmission of pathogens — in mink and found that TMPRSS2, an enzyme critical for viral fusion entry of SARS-CoV-2 in humans, is not functional in mink. Left: Prue Talbot (left) is seen with Ann Song, Right: Ann Song. (UCR/Talbot Research Group) “We found mink lung cells are infected by the ‘endocytosis pathway,’ not the TMPRSS2 fusion pathway commonly observed in human cells,” said doctoral student Ann Song, first author of the research paper that appears in Frontiers in Microbiology. “Our findings show that SARS-CoV-2 entry is not the same in all mammals and emphasize the need for thorough investigations into viral entry mechanisms across different species.” Song explained that viral fusion occurs when the membrane of the virus fuses with the plasma membrane of the host cell during infection. She said endocytosis is an essential process in which cells engulf external materials in small vesicles formed from their plasma membranes. SARS-CoV-2 can be taken up by host cells via endocytosis, she said. “Our results show that the functional — or enzymatic — domain is missing in mink TMPRSS2,” she said. “We do not know why. We think the enzyme may have multiple functions. It can do something else in mink, but it does not play a role in SARS-CoV-2 fusion to host cells. As a result, targeting TMPRSS2 would not be helpful in preventing infection in mink. What is clear is that SARS-CoV-2 entry varies among different species and tissue types.” Song said zoonosis is a public health concern as dangerous mutated forms of the virus could be introduced into the human population through spillback. During the pandemic, hundreds of papers were published on COVID-19 in humans. Now that COVID-19 in humans is under better control, scientific attention is turning to zoonosis. Lead author Prue Talbot, a professor of the graduate division in the Department of Molecular, Cell and Systems Biology in whose lab Song works, said researchers should not underestimate the possibility of spillover and spillback of SARS-CoV-2 in other mammalian species. “Deadly mutants can emerge from spillover/spillback events,” Talbot said. “As another example, many herds of deer, which are hunted by humans, are infected with SARS-CoV-2 and are thus potential sources of spillback.” Talbot and Song were joined in the research by postdoctoral researcher Rattapol Phandthong. Next, the research team will work on the infectability of human embryos in pregnant women who have COVID-19. To achieve their results, the researchers conducted their experiments using lung epithelial cells from mink. The research was supported by the Tobacco-Related Disease Research Program of the University of California, California Institute for Regenerative Medicine, and UCR. The title of the paper is “Endocytosis inhibitors block SARS-CoV-2 pseudoparticle infection of mink lung epithelium.”

Phoenix officer donates blood less than a year after being shot on the job

PHOENIX — Less than a year ago, Phoenix Police Department Officer Morgan Bullis was receiving blood transfusions as part of her recovery after being shot on the job. On Tuesday, she took part in giving the gift of life that helped save her own. In March 2023, the officer was shot in the hip and suffered injuries to her face from shrapnel during an incident near 7th and Southern avenues. At the time of her injury, the 26-year-old officer had been with the Phoenix Police Department for less than a year. Several months of recovery went by and Officer Bullis returned to her job in July. Officer Bullis was among multiple first responders who sat in blood donation chairs Tuesday during a Vitalant event to kick off their holiday blood drive. “Every day, my fellow brothers and sisters face difficult and dangerous situations in the line of duty,” said Officer Bullis. “A strong blood supply can make the difference of living and being able to go home.” Police officers and firefighters were invited by Vitalant to roll up their sleeves at the Hall of Flame museum. Vitalant representatives say every day, over 600 blood donors are needed to meet the needs of our state’s hospitals. ”We’re getting ready to enter our toughest week of the year for blood supply, basically the week between Christmas and New Years,” said Sue Thew with Vitalant. You can find out how to give blood through Vitalant by clicking here. Those who donate blood from Dec. 1-10 will receive a voucher for a complimentary admission to the Hall of Flame Fire Museum. You can also get a $10 gift card when you donate through Dec. 17.

On Giving Tuesday, Red Cross gives thanks to area blood donors

On Giving Tuesday, Red Cross gives thanks to area blood donors – CBS Chicago Watch CBS News The Red Cross needs to collect about 1,200 donations in the Chicago area. It opened two new permanent facilities in Schaumburg and Orland Park. CBS 2’s Irika Sargent found donors rolling up their sleeves – over and over again. View CBS News In Be the first to know Get browser notifications for breaking news, live events, and exclusive reporting. Not Now Turn On