Learn how a medical device company scaled its post-market trial for cardiovascular grafts and patches to meet new EU MDR requirements during the global pandemic. With a flexible approach, IQVIA MedTech used its cardiovascular post-market clinical experience to exceed patient enrollment goals six months ahead of schedule. Discover how IQVIA MedTech: Activated 31 sites across seven countries Helped the sponsor maintain EU MDR compliance on five legacy medical devices Leveraged its therapeutic area expertise to enroll and retain over 1,600 patients for a post-market cardiovascular trial that required long-term follow-up
Month: September 2023
Tue, 05 Sep 2023 19:34:35 GMT (1693942475011) f21546d3a7b92848c6890935ca4e2b625f015352 4a6d0bb8f30f1b6a167248fbd029e9fd6e7edbb4 by Jennifer Emert Tue, September 5th 2023, 11:39 AM UTC Summer might be winding down, but mosquitoes haven’t gotten the memo. (Photo Credit: Consumer Reports) Loading …
Photo by Daniel Leal / AFP via Getty Images After the last wave in March and April, there has been a sustained period of extremely low Covid infection rates in the UK over the summer – so much so that it has felt like the virus has finally gone. The relief in society at large has been palpable. The only things that might adversely affect schools and hospitals now are industrial unrest and disintegrating 1970s concrete. The sense that the pandemic is over was reinforced by the downgrading of the autumn vaccination programme. While boosters are still being made available to health and social-care workers and the clinically vulnerable, age eligibility has been restricted to the over-65s, whereas last year anyone older than 50 could get a shot. And the government slashed the fee for administering the jab, leaving many GP practices wondering if it was economically feasible even to take part in the campaign. [See also: Labour will inherit the chaos of the Covid inquiry] The messaging – that Covid is much less of a concern – was still being digested by GPs when there was a remarkable volte-face. The government abruptly bumped up the vaccination fee again, but only if surgeries started vaccinating quickly. The sudden urgency comes amid signs that a new wave is under way earlier than anticipated. The Office for National Statistics Covid Infection Survey, which used to give reliable estimates of rates of infection in the community, was disbanded in March. But many, perhaps most, readers will know someone who’s come down with Covid again in the past few weeks. And what objective data we do still have – hospital admissions and death rates – confirm the anecdotal reports that infections are on the rise. Isn’t this, though, what was expected? As the virus and the population evolve into a state of coexistence, Covid will become just another endemic illness akin to flu, with a wave every autumn and winter followed by a lull during the rest of the year. So why the sudden edginess in government quarters? The answer is: we don’t yet trust the virus not to pull a nasty trick out of the evolutionary hat. We are starting to see cases of a new, highly mutated Omicron descendant called Pirola. This has been detected in numerous countries in Europe, North America, Africa and Asia, implying efficient transmissibility. And some of the UK cases to date have had no relevant travel history, suggesting Pirola is already making its way through the community here. Although nobody yet knows whether 30-odd Pirola mutations will be able to evade the immunity built up by jabs and past infections, they are less likely to succeed when faced with an immune response that has been recently heightened by a booster shot. Hence the sudden imperative to crack on with vaccinating. There is no prospect of a return to the social restrictions of yesteryear. While the first lockdown in March 2020 aborted an unfolding crisis beyond most people’s imagination, there is a growing appreciation that the side-effects of subsequent restrictions – on psychological health, economic activity and the management of non-Covid illness – exacted a disproportionate toll. The amount of population immunity that’s been built up through successive vaccination campaigns and prior infections should continue to limit severe disease and deaths, though it will not prevent infection. As a society we are stuck in a no-man’s land. We remember with a collective shudder the exigencies of social restrictions and mandatory mask-wearing and seem determined not to yield to any measure, however benign, that might look like we’re in any way perturbed about the virus. The coercion on parents to enforce 100 per cent school attendance has returned with a vengeance, teaching children that transmission of infectious illness to others is not a concern, and nor is rest and recuperation a sensible idea when unwell. In the workplace, too, viruses are once again being brought in to be shared around. People who still wear masks are frequently stigmatised. Policies that could have put in place measures like enhanced ventilation, shown to minimise indoor transmission, have never been enacted. To the hundreds of thousands of people affected by long Covid, so many of whom previously enjoyed robust good health and economic productivity, this will seem reckless. Long Covid has never featured in the governmental calculus as to the true impact of the pandemic, mainly because data on its incidence have never been collected. But it is there in the statistics all the same, buried among the swollen numbers of people off work with long-term sickness and claiming disability benefits, many from the health and social care sectors. Most concerningly, the NHS no longer has a consistent policy for infection control. Hospital colleagues with Covid over the past few weeks report bizarre guidance: stay away if you have a high temperature or feel unwell, but otherwise it’s up to the individual to decide whether to come in. Vaccination may have reduced rates of severe illness and death, but where it still occurs is among the elderly and those with co-morbidities – people found in great numbers in healthcare settings. In wider society, it has become anathema to suggest we’re doing anything other than blithely “living with Covid”. Within the NHS we owe it to patients to continue to treat the virus with the respect it deserves. [See also: How to save the NHS] Topics in this article : Covid-19 , Healthcare , Magazine , NHS , Omicron
Royal Blood is flowing in the U.K., where the British rock duo is favorite for the chart crown with Back to the Water Below (via Warner Records). Comprising Mike Kerr and Ben Thatcher, Royal Blood takes a solid advantage into the second half of the week. According to the Official Charts Company, Back to the Water Below is currently outselling its nearest rival, The 1975’s self-titled LP, by a ratio of more than 2 to 1. If it stays on course, Back to the Water Below will mark Royal Blood’s fourth consecutive leader, a streak that dates back to, and includes, their eponymously titled debut from 2014. Explore See latest videos, charts and news See latest videos, charts and news The 1975 (Dirty Hit/Polydor) blasts to No. 2 on the midweek tally thanks to a multi-format reissue, timing to celebrate its 10th anniversary. The album originally debuted at No. 1 following its release in 2013, triggering the British band’s own streak of five consecutive No. 1 studio albums. A midweek podium place is snagged by Everything Is Alive (Dead Oceans), the fifth album from veteran British shoegaze exponents Slowdive. It’s new at No. 3 on the Official Chart Update, and is set to give the Reading-raised band their first appearance in the U.K. top 10. Slowdive has cracked the top 40 on two occasions, with 1991’s Just for a Day (No. 32) and their 2017 comeback effort, Slowdive (No. 17). Meanwhile, Sigur Rós’s latest release Atta (BMG) is on track for a No. 4 debut, for what would be the Icelandic act’s fourth top 10 appearance on the national tally. Further down the chart blast, Jethro Tull’s 14th studio album The Broadsword and the Beast (Parlophone) is poised for a return at No. 6, thanks to its 40th anniversary reissue. The album peaked at No. 27 after its original release back in 1982. Also eyeing a top 10 berth is Rivers of Heresy (Roadrunner), the first album from Empire State Bastard, a collaboration of Biffy Clyro vocalist Simon Neal and former Oceansize frontman Mike Vennart. It’s new at No. 7 on the midweek chart. Finally, veteran Scottish pop band Deacon Blue could bag a seventh top 10 album with All The 45s: The Very Best of Deacon Blue (Cooking Vinyl). The career retrospective is set to drop in at No. 8, just in time for Deacon Blue’s new U.K. tour. All will be revealed when the Official U.K. Albums Chart is published late Friday, Sept. 8.
Sign up for a full digest of all the best opinions of the week in our Voices Dispatches email Sign up to our free weekly Voices newsletter About one in three men worldwide over the age of 15 are infected with at least one type of a particular sexually transmitted infection, according to a new study. The genital human papilloma virus (HPV) is a group of viruses that affect the skin and the moist membranes lining the human body, such as the cervix, anus, mouth and throat. The research, published recently in The Lancet Global Health journal, also found that about one in five men of this age range are infected with one or more of what are known as high risk, cancer-causing HPV types. Of the over 100 different types of HPV known, about 30 can affect the genital area, making this group of viruses the second most common sexually transmitted infection in the UK. However, one of the main misconceptions about the virus is that HPV only affects women. Doctors caution that a majority of people are likely to contract HPV in their lifetime “regardless of gender”. The prevalence of genital HPV infection in the general male population, based on studies published between 1995 and 2022, was assessed by researchers, including those from the Catalan Institute of Oncology–IDIBELL in Spain in the new review of studies. They found the global pooled prevalence was 31 per cent for any HPV, and about 21 per cent for high-risk HPV. “Our findings show that HPV prevalence is high in men over the age of 15 years and support that sexually active men, regardless of age, are an important reservoir of HPV genital infection,” scientists wrote in the study. They also found that HPV-16 was the most prevalent HPV genotype followed by HPV-6. The analysis revealed HPV was most prevalent in young adults, reaching a maximum between the ages of 25 and 29 years, and stabilising or slightly decreasing among older populations. The estimates for eastern and southeastern Asia, according to the new study, were half that of the other regions. While a majority of HPV infections in men and women do not present symptoms, they can lead to long-term injury and mortality with over 340,000 women dying of cervical cancer due to HPV, according to the World Health Organization. In men, HPV infection may lead to anogenital warts that cause significant morbidity and increase HPV transmission rates. Infection with HPV is also linked with penile, anal and oropharyngeal cancers – commonly linked to HPV type 16, researchers said. About 69,400 cases of cancer in men were caused by HPV in 2018, they said. “This global study on the prevalence of genital HPV infection among men confirms how widespread HPV infection is. HPV infection with high-risk HPV types can cause genital warts and oral, penile and anal cancer in men,” said Meg Doherty, Director of WHO’s Global HIV, Hepatitis and Sexually Transmitted Infections Programs. “These estimates emphasise the importance of incorporating men in comprehensive HPV prevention strategies to reduce HPV-related morbidity and mortality in men and ultimately achieve elimination of cervical cancer and other HPV-related diseases,” researchers noted.
September month is dedicated to honoring those who have survived blood cancer and also aims at creating awareness about the disease. An important part of cancer treatment is awareness and access to the right information. Very often we come across myths around major diseases which delay the diagnosis and treatment of the disease. We spoke to Dr. Niti Krishna Raizada, Senior Director, Medical Oncology & Hemato-Oncology, Fortis Hospitals, Richmond Road, Bangalore to shed light on different myths and facts about blood cancer. “There are several myths and misconceptions surrounding blood cancer, also known as hematologic cancer. It’s essential to dispel these myths to promote accurate understanding and provide support for individuals affected by these diseases. Here are some common myths and the facts that debunk them,” says Dr. Raizada.
#inform-video-player-1 .inform-embed { margin-top: 10px; margin-bottom: 20px; } #inform-video-player-2 .inform-embed { margin-top: 10px; margin-bottom: 20px; } “As certain as it is that blood is always red and Kentucky grass is always blue, the need for blood is always present,” the Kentucky Blood Center said in a Friday news release. The organization said donors can help meet the constant need at an upcoming blood drive. The drive is being held at Baptist Health Paducah’s Heart Barnes Auditorium from 3-5:30 p.m. Sept. 13 and 7a.m.-4 p.m. Sept. 14. KBC says all registered donors at the upcoming drive will receive a “Blood is Red, Grass is Blue, I Save Lives, How ‘Bout You” T-shirt while supplies last. According to KBC, one in four people will need a blood transfusion in their lifetime. Through the generosity of donors, KBC provides blood for a wide range of vital treatments, including cancer, trauma, sickle cell, organ transplant, surgeries and much more, the release explains. According to the release, blood donors must be at least 17-years-old (16 with parental consent), weigh at least 110 pounds, be in general good health, show a photo I.D. and meet additional requirements. Sixteen-year-old donors must have a signed parental permission slip, which can be found at kybloodcenter.org. KBC said appointments are preferred but walk-ins are welcome. To schedule a donation, visit kybloodcenter.org or call 800-775-2522. #inform-video-player-3 .inform-embed { margin-top: 10px; margin-bottom: 20px; }
DUBOIS – The need for blood in the Tri-County area is constant, but sometimes that need becomes critical. Now is one of those times. You have a chance to make a difference by donating blood today in DuBois. The American Red Cross is having a blood drive at the DuBois Area YMCA on Parkway Drive from 12 Noon until 5:30 this afternoon.
COVID-19 Infection Rates in Vaccinated and Unvaccinated Inmates: A Retrospective Cohort Study
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